docusate sodium mechanism of action
Docusate is an anionic surfactant that helps lower the surface tension at the oil-water interface of the stool and thus allows water and lipids or fats to enter the stool. The Comprehensive Pharmacology Reference 2007.
Psyllium Is Superior To Docusate Sodium For Treatment Of Chronic Constipation Mcrorie 1998 Alimentary Pharmacology Amp Therapeutics Wiley Online Library
Docusate is available under the following different brand names.

. These cathartics absorb water and provide bulk for the gastrointestinal tract. It works by increasing the amount of water the stool absorbs in the gut making the stool softer and easier to pass. Docusate is an anionic surfactant ie a surface-active agent. 12 to 72 hours.
This helps to hydrate and soften the fecal material facilitating natural defecation. Pharmacokinetics and Mechanism of Action. It lowers the surface tension and allows. Dioctyl Sodium Sulfosuccinate - Pharmacokinetics and Mechanism of Action.
Feces Gattuso 1994 Onset of Action. This medication promotes incorporation of water into stool resulting in softer fecal mass and easier passage of stool. It lowers the surface tension at the oil-water interface of the feces allowing water and lipids to penetrate the stool. Reduces surface tension of the oil-water interface of the stool resulting in stool softening.
Docusates onset of action is 6-72 hours orally and 2-15 minutes rectally. Docusate is a commonly used non-prescription OTC or over-the-counter stool softener used to treat or prevent constipation. Docusate sodium is a laxative and an anionic detergent that supposedly promotes incorporation of water and fats into stool through a reduction in surface tension resulting in softer fecal mass 64. Docusate sodium is a laxative and an anionic detergent that supposedly promotes incorporation of water and fats into stool through a reduction in surface tension resulting in softer fecal mass.
Docusate sodium Mechanism of Action. Docusate Sodium What is the mechanism of action. Docusate does not stay in the gastrointestinal tract but is absorbed into the bloodstream and excreted via the gallbladder after undergoing extensive metabolism. It works by increasing the amount of water the.
Docusate is an anionic surfactant ie a surface-active agent. Docusate is an emollient stool softener surfactant laxatives. Docusate is an emollient stool softener surfactant laxatives. Docusate Sodium is the sodium salt of docusate a dioctyl salt and an emollient laxative with stool-softening activity.
As a result it softens the stool. 2 to 15 minutes. What is the therapeutic category. Mechanism of Action.
Docusate sodium lowers the surface tension of the stool allowing the mixing of aqueous and fatty substances softening the stool and permitting easier defecation. By lowering the surface tension of the oil-water interface of the stool it allows the passage of water and lipids into the stool mass. Mechanism of Action. The increased bulk provides stimulation to the.
Colace DSS Albert Docusate Docusate Calcium docusate sodium DulcoEase Phillips Liqui Gels Silace and Soflax. By lowering the surface tension of the oil-water interface of the stool it allows the passage of water and lipids into the stool mass. The mechanisms of action are important because the physician may select a particular agent because of the specific favorable results obtained as a direct effect of a mechanism of action. Docusate sodium is also used off-label as a ceruminolytic.
Docusate sodium an anionic surfactant is a stool softener that also possesses a stimulant activity. Docusate is a stool softener. Docusate sodium dioctyl sodium sulfosuccinate and docusate calcium dioctyl calcium sulfosuccinate act like detergents and are used to soften the stool when it is desirable to lessen the discomfort or the strain of defecation. Reduces surface tension of the oil-water interface of the stool resulting in enhanced incorporation of water and fat allowing for stool softening Roering 2010 PharmacokineticsPharmacodynamics Excretion.
It lowers the surface tension at the oil-water interface of the feces allowing water and lipids to penetrate the stool. Docusate lowers the surface tension at the oil water interface of the feces allowing water and lipids to penetrate the stool. Terms in this set 12 1. This stimulant laxative-stool softener combination works synergistically to relieve constipation.
This helps to hydrate and soften the fecal material facilitating natural defecation. As a result the stool softens and passes easily through the intestinal tract. Docusate decreases surface tension and emulsification of fecal matter and allows water to penetrate and mix with stool. Docusate is often used when straining to have a bowel movement should be avoided eg after a heart attack or surgeryDocusate is a stool softener.
Moa MECHANISM OF ACTION a. Docusates onset of action is 6-72 hours orally and 2-15 minutes rectally 6 7. What is docusate-oral and how does it work mechanism of action.
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